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U3 small nucleolar RNA-associated protein 4 homolog (UTP4)

Homo sapiens — UniProt Q969X6

Gene: UTP4Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

U3 small nucleolar RNA-associated protein 4 homolog (UTP4) is a protein from Homo sapiens identified by UniProt accession Q969X6, 686 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

  • UniProt accession: Q969X6; gene symbol UTP4.
  • Organism: Homo sapiens.
  • Length: 686 amino acids.
  • Top disease associations (Open Targets): hereditary North American Indian childhood cirrhosis, body mass index and lean body mass.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameU3 small nucleolar RNA-associated protein 4 homolog
UniProt accessionQ969X6
GeneUTP4
OrganismHomo sapiens
Length686 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (43)

Diseases linked to this target (Open Targets).

  • hereditary North American Indian childhood cirrhosis · score 0.42
  • body mass index · score 0.13
  • lean body mass · score 0.12
  • cortical thickness · score 0.11
  • alcohol consumption measurement · score 0.10
  • body height · score 0.09
  • diastolic blood pressure · score 0.08
  • body fat percentage · score 0.07
  • isolated asymptomatic elevation of creatine phosphokinase · score 0.07
  • health study participation · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q969X6-F1alphafoldPREDICTED91.21—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q969X6.

Amino-acid sequence (686 residues)

MGEFKVHRVR FFNYVPSGIR CVAYNNQSNR LAVSRTDGTV EIYNLSANYF QEKFFPGHES RATEALCWAE GQRLFSAGLN GEIMEYDLQA LNIKYAMDAF GGPIWSMAAS PSGSQLLVGC EDGSVKLFQI TPDKIQFERN FDRQKSRILS LSWHPSGTHI AAGSIDYISV FDVKSGSAVH KMIVDRQYMG VSKRKCIVWG VAFLSDGTII SVDSAGKVQF WDSATGTLVK SHLIANADVQ SIAVADQEDS FVVGTAEGTV FHFQLVPVTS NSSEKQWVRT KPFQHHTHDV RTVAHSPTAL ISGGTDTHLV FRPLMEKVEV KNYDAALRKI TFPHRCLISC SKKRQLLLFQ FAHHLELWRL GSTVATGKNG DTLPLSKNAD HLLHLKTKGP ENIICSCISP CGSWIAYSTV SRFFLYRLNY EHDNISLKRV SKMPAFLRSA LQILFSEDST KLFVASNQGA LHIVQLSGGS FKHLHAFQPQ SGTVEAMCLL AVSPDGNWLA ASGTSAGVHV YNVKQLKLHC TVPAYNFPVT AMAIAPNTNN LVIAHSDQQV FEYSIPDKQY TDWSRTVQKQ GFHHLWLQRD TPITHISFHP KRPMHILLHD AYMFCIIDKS LPLPNDKTLL YNPFPPTNES DVIRRRTAHA FKISKIYKPL LFMDLLDERT LVAVERPLDD IIAQLPPPIK KKKFGT

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with UTP4?

The strongest Open Targets associations for UTP4 are hereditary North American Indian childhood cirrhosis, body mass index, lean body mass, cortical thickness and alcohol consumption measurement.

How long is the UTP4 protein?

The Homo sapiens UTP4 protein (UniProt Q969X6) is 686 amino acids long.

Browse: Targets: U · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ969X6
GeneUTP4
OrganismHomo sapiens
Length686
Binders0
Diseases43
View on UniProt