Protein phosphatase 1 regulatory subunit 14A…

About Protein phosphatase 1 regulatory subunit 14A

Protein phosphatase 1 regulatory subunit 14A (PPP1R14A) is a protein from Homo sapiens identified by UniProt accession Q96A00, 147 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.

Target properties

Protein name	Protein phosphatase 1 regulatory subunit 14A
UniProt accession	Q96A00
Gene	PPP1R14A
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (102)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.34
prostate carcinoma · score 0.24
diverticular disease · score 0.21
male reproductive organ cancer · score 0.20
cancer · score 0.17
prostate cancer · score 0.16
diverticulitis · score 0.16
serum alanine aminotransferase measurement · score 0.15
aspartate aminotransferase to alanine aminotransferase ratio · score 0.08
melanoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96A00-F1	alphafold	PREDICTED	60.05	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A00.

Amino-acid sequence (147 residues)

MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Protein phosphatase 1 regulatory subunit 14A (PPP1R14A)