Galactose-3-O-sulfotransferase 3 (GAL3ST3)
Homo sapiens — UniProt Q96A11
Data last refreshed: (UniProt release unknown)
Key facts
Galactose-3-O-sulfotransferase 3 (GAL3ST3) is a protein from Homo sapiens identified by UniProt accession Q96A11, 431 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q96A11; gene symbol GAL3ST3.
- Organism: Homo sapiens.
- Length: 431 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Red cell distribution width and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Galactose-3-O-sulfotransferase 3 |
|---|---|
| UniProt accession | Q96A11 |
| Gene | GAL3ST3 |
| Organism | Homo sapiens |
| Length | 431 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- Red cell distribution width · score 0.28
- serum alanine aminotransferase measurement · score 0.09
- reticulocyte count · score 0.07
- reticulocyte measurement · score 0.04
- bipolar I disorder · score 0.02
- bipolar disorder · score 0.02
- C-reactive protein measurement · score 0.02
- vital capacity · score 0.02
- pituitary cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A11-F1 | alphafold | PREDICTED | 86.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A11.
Amino-acid sequence (431 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GAL3ST3?
The strongest Open Targets associations for GAL3ST3 are neurodegenerative disease, Red cell distribution width, serum alanine aminotransferase measurement, reticulocyte count and reticulocyte measurement.
How long is the GAL3ST3 protein?
The Homo sapiens GAL3ST3 protein (UniProt Q96A11) is 431 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A11 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A11 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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