Copine-4 (CPNE4)
Homo sapiens — UniProt Q96A23
Data last refreshed: (UniProt release unknown)
Key facts
Copine-4 (CPNE4) is a protein from Homo sapiens identified by UniProt accession Q96A23, 557 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q96A23; gene symbol CPNE4.
- Organism: Homo sapiens.
- Length: 557 amino acids.
- Top disease associations (Open Targets): body mass index, high density lipoprotein cholesterol measurement and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Copine-4 |
|---|---|
| UniProt accession | Q96A23 |
| Gene | CPNE4 |
| Organism | Homo sapiens |
| Length | 557 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- body mass index · score 0.46
- high density lipoprotein cholesterol measurement · score 0.38
- smoking status measurement · score 0.38
- age at first sexual intercourse measurement · score 0.38
- body fat percentage · score 0.36
- lean body mass · score 0.35
- mathematical ability · score 0.34
- body height · score 0.33
- waist-hip ratio · score 0.32
- fat body mass · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A23-F1 | alphafold | PREDICTED | 87.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A23.
Amino-acid sequence (557 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CPNE4?
The strongest Open Targets associations for CPNE4 are body mass index, high density lipoprotein cholesterol measurement, smoking status measurement, age at first sexual intercourse measurement and body fat percentage.
How long is the CPNE4 protein?
The Homo sapiens CPNE4 protein (UniProt Q96A23) is 557 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A23 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A23 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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