GDP-fucose transporter 1 (SLC35C1)
Homo sapiens — UniProt Q96A29
Data last refreshed: (UniProt release unknown)
Key facts
GDP-fucose transporter 1 (SLC35C1) is a protein from Homo sapiens identified by UniProt accession Q96A29, 364 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.
- UniProt accession: Q96A29; gene symbol SLC35C1.
- Organism: Homo sapiens.
- Length: 364 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): leukocyte adhesion deficiency type II, congenital disorder of glycosylation and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GDP-fucose transporter 1 |
|---|---|
| UniProt accession | Q96A29 |
| Gene | SLC35C1 |
| Organism | Homo sapiens |
| Length | 364 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (78)
Diseases linked to this target (Open Targets).
- leukocyte adhesion deficiency type II · score 0.79
- congenital disorder of glycosylation · score 0.53
- neurodegenerative disease · score 0.46
- Alzheimer disease · score 0.39
- congenital disorder of glycosylation type II · score 0.37
- multiple sclerosis · score 0.37
- lysosomal storage disease · score 0.37
- Parkinson disease · score 0.37
- type 2 diabetes mellitus · score 0.24
- genetic disorder · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A29-F1 | alphafold | PREDICTED | 82.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A29.
Amino-acid sequence (364 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC35C1?
The strongest Open Targets associations for SLC35C1 are leukocyte adhesion deficiency type II, congenital disorder of glycosylation, neurodegenerative disease, Alzheimer disease and congenital disorder of glycosylation type II.
How long is the SLC35C1 protein?
The Homo sapiens SLC35C1 protein (UniProt Q96A29) is 364 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A29 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A29 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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