Myosin regulatory light chain 11 (MYL11)
Homo sapiens — UniProt Q96A32
Data last refreshed: (UniProt release unknown)
Key facts
Myosin regulatory light chain 11 (MYL11) is a protein from Homo sapiens identified by UniProt accession Q96A32, 169 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q96A32; gene symbol MYL11.
- Organism: Homo sapiens.
- Length: 169 amino acids.
- Top disease associations (Open Targets): arthrogryposis, distal, type 1C, distal arthrogryposis and lethal congenital contracture syndrome 3.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Myosin regulatory light chain 11 |
|---|---|
| UniProt accession | Q96A32 |
| Gene | MYL11 |
| Organism | Homo sapiens |
| Length | 169 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- arthrogryposis, distal, type 1C · score 0.65
- distal arthrogryposis · score 0.37
- lethal congenital contracture syndrome 3 · score 0.05
- blood protein measurement · score 0.05
- Lethal congenital contracture syndrome type 3 · score 0.04
- Autosomal recessive limb-girdle muscular dystrophy due to ISPD deficiency · score 0.04
- congenital myopathy 2b, severe infantile, autosomal recessive · score 0.04
- congenital diaphragmatic hernia · score 0.04
- arthrogryposis multiplex congenita · score 0.04
- pontocerebellar hypoplasia type 1 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A32-F1 | alphafold | PREDICTED | 84.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A32.
Amino-acid sequence (169 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MYL11?
The strongest Open Targets associations for MYL11 are arthrogryposis, distal, type 1C, distal arthrogryposis, lethal congenital contracture syndrome 3, blood protein measurement and Lethal congenital contracture syndrome type 3.
How long is the MYL11 protein?
The Homo sapiens MYL11 protein (UniProt Q96A32) is 169 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A32 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A32 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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