Myosin regulatory light chain 11 (MYL11)

About Myosin regulatory light chain 11

Myosin regulatory light chain 11 (MYL11) is a protein from Homo sapiens identified by UniProt accession Q96A32, 169 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Myosin regulatory light chain 11
UniProt accession	Q96A32
Gene	MYL11
Organism	Homo sapiens
Length	169 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

arthrogryposis, distal, type 1C · score 0.65
distal arthrogryposis · score 0.37
lethal congenital contracture syndrome 3 · score 0.05
blood protein measurement · score 0.05
Lethal congenital contracture syndrome type 3 · score 0.04
Autosomal recessive limb-girdle muscular dystrophy due to ISPD deficiency · score 0.04
congenital myopathy 2b, severe infantile, autosomal recessive · score 0.04
congenital diaphragmatic hernia · score 0.04
arthrogryposis multiplex congenita · score 0.04
pontocerebellar hypoplasia type 1 · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96A32-F1	alphafold	PREDICTED	84.14	—

Amino-acid sequence (169 residues)

MAPKRAKRRT VEGGSSSVFS MFDQTQIQEF KEAFTVIDQN RDGIIDKEDL RDTFAAMGRL NVKNEELDAM MKEASGPINF TVFLTMFGEK LKGADPEDVI TGAFKVLDPE GKGTIKKKFL EELLTTQCDR FSQEEIKNMW AAFPPDVGGN VDYKNICYVI THGDAKDQE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards