Adiponectin receptor protein 1 (ADIPOR1)
Homo sapiens — UniProt Q96A54
Data last refreshed: (UniProt release unknown)
Key facts
Adiponectin receptor protein 1 (ADIPOR1) is a protein from Homo sapiens identified by UniProt accession Q96A54, 375 residues long. MolForge cross-references it against 0 known binders and 337 disease associations.
- UniProt accession: Q96A54; gene symbol ADIPOR1.
- Organism: Homo sapiens.
- Length: 375 amino acids.
- Top disease associations (Open Targets): lung adenocarcinoma, mean platelet volume and Retinal dystrophy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adiponectin receptor protein 1 |
|---|---|
| UniProt accession | Q96A54 |
| Gene | ADIPOR1 |
| Organism | Homo sapiens |
| Length | 375 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (337)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.19
- mean platelet volume · score 0.18
- Retinal dystrophy · score 0.15
- type 2 diabetes mellitus · score 0.11
- coronary artery disease · score 0.10
- cancer · score 0.09
- MODY · score 0.09
- neoplasm · score 0.09
- insulin resistance · score 0.08
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A54-F1 | alphafold | PREDICTED | 83.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A54.
Amino-acid sequence (375 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADIPOR1?
The strongest Open Targets associations for ADIPOR1 are lung adenocarcinoma, mean platelet volume, Retinal dystrophy, type 2 diabetes mellitus and coronary artery disease.
How long is the ADIPOR1 protein?
The Homo sapiens ADIPOR1 protein (UniProt Q96A54) is 375 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A54 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A54 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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