Tumor protein p53-inducible nuclear protein 1 (TP53INP1)
Homo sapiens — UniProt Q96A56
Data last refreshed: (UniProt release unknown)
Key facts
Tumor protein p53-inducible nuclear protein 1 (TP53INP1) is a protein from Homo sapiens identified by UniProt accession Q96A56, 240 residues long. MolForge cross-references it against 0 known binders and 166 disease associations.
- UniProt accession: Q96A56; gene symbol TP53INP1.
- Organism: Homo sapiens.
- Length: 240 amino acids.
- Top disease associations (Open Targets): HbA1c measurement, type 2 diabetes mellitus and glucose measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tumor protein p53-inducible nuclear protein 1 |
|---|---|
| UniProt accession | Q96A56 |
| Gene | TP53INP1 |
| Organism | Homo sapiens |
| Length | 240 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (166)
Diseases linked to this target (Open Targets).
- HbA1c measurement · score 0.34
- type 2 diabetes mellitus · score 0.34
- glucose measurement · score 0.34
- eosinophil count · score 0.30
- neurodegenerative disease · score 0.29
- alkaline phosphatase measurement · score 0.28
- serum gamma-glutamyl transferase measurement · score 0.28
- platelet component distribution width · score 0.28
- glioblastoma multiforme · score 0.27
- hemoglobin measurement · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A56-F1 | alphafold | PREDICTED | 57.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A56.
Amino-acid sequence (240 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TP53INP1?
The strongest Open Targets associations for TP53INP1 are HbA1c measurement, type 2 diabetes mellitus, glucose measurement, eosinophil count and neurodegenerative disease.
How long is the TP53INP1 protein?
The Homo sapiens TP53INP1 protein (UniProt Q96A56) is 240 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A56 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A56 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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