Transmembrane protein 230 (TMEM230)
Homo sapiens — UniProt Q96A57
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 230 (TMEM230) is a protein from Homo sapiens identified by UniProt accession Q96A57, 120 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q96A57; gene symbol TMEM230.
- Organism: Homo sapiens.
- Length: 120 amino acids.
- Top disease associations (Open Targets): mean platelet volume, viral load and late-onset Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 230 |
|---|---|
| UniProt accession | Q96A57 |
| Gene | TMEM230 |
| Organism | Homo sapiens |
| Length | 120 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.32
- viral load · score 0.27
- late-onset Parkinson disease · score 0.23
- body height · score 0.22
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- neurofibrillary tangles measurement · score 0.10
- glioblastoma multiforme · score 0.09
- glioma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A57-F1 | alphafold | PREDICTED | 81.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A57.
Amino-acid sequence (120 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM230?
The strongest Open Targets associations for TMEM230 are mean platelet volume, viral load, late-onset Parkinson disease, body height and prostate cancer.
How long is the TMEM230 protein?
The Homo sapiens TMEM230 protein (UniProt Q96A57) is 120 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A57 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A57 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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