Ras-related and estrogen-regulated growth inhibitor (RERG)
Homo sapiens — UniProt Q96A58
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related and estrogen-regulated growth inhibitor (RERG) is a protein from Homo sapiens identified by UniProt accession Q96A58, 199 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.
- UniProt accession: Q96A58; gene symbol RERG.
- Organism: Homo sapiens.
- Length: 199 amino acids.
- Top disease associations (Open Targets): glomerular filtration rate, creatinine measurement and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related and estrogen-regulated growth inhibitor |
|---|---|
| UniProt accession | Q96A58 |
| Gene | RERG |
| Organism | Homo sapiens |
| Length | 199 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (81)
Diseases linked to this target (Open Targets).
- glomerular filtration rate · score 0.45
- creatinine measurement · score 0.44
- urate measurement · score 0.42
- hemoglobin measurement · score 0.40
- cystatin C measurement · score 0.39
- hematocrit · score 0.39
- serum urea measurement · score 0.36
- serum gamma-glutamyl transferase measurement · score 0.36
- FEV/FVC ratio · score 0.36
- red blood cell density measurement · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A58-F1 | alphafold | PREDICTED | 90.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A58.
Amino-acid sequence (199 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RERG?
The strongest Open Targets associations for RERG are glomerular filtration rate, creatinine measurement, urate measurement, hemoglobin measurement and cystatin C measurement.
How long is the RERG protein?
The Homo sapiens RERG protein (UniProt Q96A58) is 199 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A58 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A58 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.