MARVEL domain-containing protein 3 (MARVELD3)
Homo sapiens — UniProt Q96A59
Data last refreshed: (UniProt release unknown)
Key facts
MARVEL domain-containing protein 3 (MARVELD3) is a protein from Homo sapiens identified by UniProt accession Q96A59, 401 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q96A59; gene symbol MARVELD3.
- Organism: Homo sapiens.
- Length: 401 amino acids.
- Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, urate measurement and haptoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MARVEL domain-containing protein 3 |
|---|---|
| UniProt accession | Q96A59 |
| Gene | MARVELD3 |
| Organism | Homo sapiens |
| Length | 401 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.20
- urate measurement · score 0.18
- haptoglobin measurement · score 0.18
- prostate carcinoma · score 0.18
- metabolite measurement · score 0.17
- sex hormone-binding globulin measurement · score 0.17
- HMG CoA reductase inhibitor use measurement · score 0.16
- pulse pressure measurement · score 0.14
- mean reticulocyte volume · score 0.14
- mean corpuscular volume · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A59-F1 | alphafold | PREDICTED | 66.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A59.
Amino-acid sequence (401 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MARVELD3?
The strongest Open Targets associations for MARVELD3 are low density lipoprotein cholesterol measurement, urate measurement, haptoglobin measurement, prostate carcinoma and metabolite measurement.
How long is the MARVELD3 protein?
The Homo sapiens MARVELD3 protein (UniProt Q96A59) is 401 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A59 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A59 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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