Antizyme inhibitor 2 (AZIN2)
Homo sapiens — UniProt Q96A70
Data last refreshed: (UniProt release unknown)
Key facts
Antizyme inhibitor 2 (AZIN2) is a protein from Homo sapiens identified by UniProt accession Q96A70, 460 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q96A70; gene symbol AZIN2.
- Organism: Homo sapiens.
- Length: 460 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, hyperinsulinism due to INSR deficiency and hyperproinsulinemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Antizyme inhibitor 2 |
|---|---|
| UniProt accession | Q96A70 |
| Gene | AZIN2 |
| Organism | Homo sapiens |
| Length | 460 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.09
- hyperinsulinism due to INSR deficiency · score 0.05
- hyperproinsulinemia · score 0.05
- myocardial infarction · score 0.05
- hyperinsulinism due to glucokinase deficiency · score 0.05
- exercise-induced hyperinsulinism · score 0.05
- neoplasm · score 0.04
- cancer · score 0.02
- benign prostatic hyperplasia · score 0.02
- non-small cell lung carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96A70-F1 | alphafold | PREDICTED | 83.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96A70.
Amino-acid sequence (460 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AZIN2?
The strongest Open Targets associations for AZIN2 are gut microbiome measurement, hyperinsulinism due to INSR deficiency, hyperproinsulinemia, myocardial infarction and hyperinsulinism due to glucokinase deficiency.
How long is the AZIN2 protein?
The Homo sapiens AZIN2 protein (UniProt Q96A70) is 460 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96A70 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96A70 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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