Ras-related protein Rab-7b (RAB7B)
Homo sapiens — UniProt Q96AH8
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-7b (RAB7B) is a protein from Homo sapiens identified by UniProt accession Q96AH8, 199 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q96AH8; gene symbol RAB7B.
- Organism: Homo sapiens.
- Length: 199 amino acids.
- Top disease associations (Open Targets): experimental autoimmune encephalomyelitis, monocyte count and reaction time measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-7b |
|---|---|
| UniProt accession | Q96AH8 |
| Gene | RAB7B |
| Organism | Homo sapiens |
| Length | 199 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- experimental autoimmune encephalomyelitis · score 0.04
- monocyte count · score 0.03
- reaction time measurement · score 0.03
- cortical surface area measurement · score 0.02
- brain measurement · score 0.02
- neuroimaging measurement · score 0.02
- human papilloma virus infection · score 0.02
- total blood protein measurement · score 0.02
- cortical thickness · score 0.02
- IGF-1 measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96AH8-F1 | alphafold | PREDICTED | 88.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96AH8.
Amino-acid sequence (199 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB7B?
The strongest Open Targets associations for RAB7B are experimental autoimmune encephalomyelitis, monocyte count, reaction time measurement, cortical surface area measurement and brain measurement.
How long is the RAB7B protein?
The Homo sapiens RAB7B protein (UniProt Q96AH8) is 199 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96AH8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96AH8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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