Clusterin-associated protein 1 (CLUAP1)
Homo sapiens — UniProt Q96AJ1
Data last refreshed: (UniProt release unknown)
Key facts
Clusterin-associated protein 1 (CLUAP1) is a protein from Homo sapiens identified by UniProt accession Q96AJ1, 413 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q96AJ1; gene symbol CLUAP1.
- Organism: Homo sapiens.
- Length: 413 amino acids.
- Top disease associations (Open Targets): Leber congenital amaurosis, Joubert syndrome and creatinine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Clusterin-associated protein 1 |
|---|---|
| UniProt accession | Q96AJ1 |
| Gene | CLUAP1 |
| Organism | Homo sapiens |
| Length | 413 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- Leber congenital amaurosis · score 0.46
- Joubert syndrome · score 0.32
- creatinine measurement · score 0.29
- cystatin C measurement · score 0.27
- vital capacity · score 0.27
- serum gamma-glutamyl transferase measurement · score 0.24
- systolic blood pressure · score 0.23
- cardiovascular disease · score 0.22
- diastolic blood pressure · score 0.22
- hypertension · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96AJ1-F1 | alphafold | PREDICTED | 77.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96AJ1.
Amino-acid sequence (413 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLUAP1?
The strongest Open Targets associations for CLUAP1 are Leber congenital amaurosis, Joubert syndrome, creatinine measurement, cystatin C measurement and vital capacity.
How long is the CLUAP1 protein?
The Homo sapiens CLUAP1 protein (UniProt Q96AJ1) is 413 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96AJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96AJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.