Vesicle transport through interaction with t-SNAREs homolog 1A (VTI1A)
Homo sapiens — UniProt Q96AJ9
Data last refreshed: (UniProt release unknown)
Key facts
Vesicle transport through interaction with t-SNAREs homolog 1A (VTI1A) is a protein from Homo sapiens identified by UniProt accession Q96AJ9, 217 residues long. MolForge cross-references it against 0 known binders and 211 disease associations.
- UniProt accession: Q96AJ9; gene symbol VTI1A.
- Organism: Homo sapiens.
- Length: 217 amino acids.
- Top disease associations (Open Targets): colorectal cancer, heel bone mineral density and QRS duration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vesicle transport through interaction with t-SNAREs homolog 1A |
|---|---|
| UniProt accession | Q96AJ9 |
| Gene | VTI1A |
| Organism | Homo sapiens |
| Length | 217 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (211)
Diseases linked to this target (Open Targets).
- colorectal cancer · score 0.40
- heel bone mineral density · score 0.34
- QRS duration · score 0.30
- electrocardiography · score 0.26
- colorectal adenoma · score 0.26
- age at first sexual intercourse measurement · score 0.25
- polyp of large intestine · score 0.25
- smoking status measurement · score 0.25
- attention deficit hyperactivity disorder · score 0.25
- antisocial behaviour measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96AJ9-F1 | alphafold | PREDICTED | 84.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96AJ9.
Amino-acid sequence (217 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VTI1A?
The strongest Open Targets associations for VTI1A are colorectal cancer, heel bone mineral density, QRS duration, electrocardiography and colorectal adenoma.
How long is the VTI1A protein?
The Homo sapiens VTI1A protein (UniProt Q96AJ9) is 217 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96AJ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96AJ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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