Coiled-coil domain-containing protein 74A (CCDC74A)
Homo sapiens — UniProt Q96AQ1
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 74A (CCDC74A) is a protein from Homo sapiens identified by UniProt accession Q96AQ1, 378 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q96AQ1; gene symbol CCDC74A.
- Organism: Homo sapiens.
- Length: 378 amino acids.
- Top disease associations (Open Targets): adolescent idiopathic scoliosis, arterial stiffness measurement and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 74A |
|---|---|
| UniProt accession | Q96AQ1 |
| Gene | CCDC74A |
| Organism | Homo sapiens |
| Length | 378 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.27
- arterial stiffness measurement · score 0.02
- neoplasm · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96AQ1-F1 | alphafold | PREDICTED | 59.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96AQ1.
Amino-acid sequence (378 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC74A?
The strongest Open Targets associations for CCDC74A are adolescent idiopathic scoliosis, arterial stiffness measurement, neoplasm and cancer.
How long is the CCDC74A protein?
The Homo sapiens CCDC74A protein (UniProt Q96AQ1) is 378 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96AQ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96AQ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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