Pre-B-cell leukemia transcription factor-interacting protein 1 (PBXIP1)
Homo sapiens — UniProt Q96AQ6
Data last refreshed: (UniProt release unknown)
Key facts
Pre-B-cell leukemia transcription factor-interacting protein 1 (PBXIP1) is a protein from Homo sapiens identified by UniProt accession Q96AQ6, 731 residues long. MolForge cross-references it against 0 known binders and 186 disease associations.
- UniProt accession: Q96AQ6; gene symbol PBXIP1.
- Organism: Homo sapiens.
- Length: 731 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, prostate carcinoma and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pre-B-cell leukemia transcription factor-interacting protein 1 |
|---|---|
| UniProt accession | Q96AQ6 |
| Gene | PBXIP1 |
| Organism | Homo sapiens |
| Length | 731 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (186)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.25
- prostate carcinoma · score 0.13
- PHF-tau measurement · score 0.12
- Parkinson disease · score 0.12
- erythrocyte count · score 0.11
- gonorrhea · score 0.07
- microphthalmia with limb anomalies · score 0.07
- upper limb mesomelic dysplasia · score 0.06
- Gollop-Wolfgang complex · score 0.06
- metaphyseal anadysplasia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96AQ6-F1 | alphafold | PREDICTED | 57.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96AQ6.
Amino-acid sequence (731 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PBXIP1?
The strongest Open Targets associations for PBXIP1 are FEV/FVC ratio, prostate carcinoma, PHF-tau measurement, Parkinson disease and erythrocyte count.
How long is the PBXIP1 protein?
The Homo sapiens PBXIP1 protein (UniProt Q96AQ6) is 731 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96AQ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96AQ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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