Mitochondrial calcium uniporter regulator 1 (MCUR1)
Homo sapiens — UniProt Q96AQ8
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial calcium uniporter regulator 1 (MCUR1) is a protein from Homo sapiens identified by UniProt accession Q96AQ8, 359 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q96AQ8; gene symbol MCUR1.
- Organism: Homo sapiens.
- Length: 359 amino acids.
- Top disease associations (Open Targets): intelligence, hepatocellular carcinoma and triple-negative breast cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial calcium uniporter regulator 1 |
|---|---|
| UniProt accession | Q96AQ8 |
| Gene | MCUR1 |
| Organism | Homo sapiens |
| Length | 359 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- intelligence · score 0.20
- hepatocellular carcinoma · score 0.10
- triple-negative breast cancer · score 0.04
- 1,5 anhydroglucitol measurement · score 0.03
- type 2 diabetes mellitus · score 0.03
- cancer · score 0.02
- Invasive Breast Carcinoma · score 0.02
- neoplasm · score 0.02
- periodontitis · score 0.01
- juvenile dermatomyositis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96AQ8-F1 | alphafold | PREDICTED | 69.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96AQ8.
Amino-acid sequence (359 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MCUR1?
The strongest Open Targets associations for MCUR1 are intelligence, hepatocellular carcinoma, triple-negative breast cancer, 1,5 anhydroglucitol measurement and type 2 diabetes mellitus.
How long is the MCUR1 protein?
The Homo sapiens MCUR1 protein (UniProt Q96AQ8) is 359 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96AQ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96AQ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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