Ras-related protein Rab-37 (RAB37)
Homo sapiens — UniProt Q96AX2
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-37 (RAB37) is a protein from Homo sapiens identified by UniProt accession Q96AX2, 223 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.
- UniProt accession: Q96AX2; gene symbol RAB37.
- Organism: Homo sapiens.
- Length: 223 amino acids.
- Top disease associations (Open Targets): platelet count, lymphocyte count and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-37 |
|---|---|
| UniProt accession | Q96AX2 |
| Gene | RAB37 |
| Organism | Homo sapiens |
| Length | 223 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (92)
Diseases linked to this target (Open Targets).
- platelet count · score 0.36
- lymphocyte count · score 0.35
- neurodegenerative disease · score 0.33
- platelet crit · score 0.32
- blood protein measurement · score 0.31
- leukocyte count · score 0.29
- monocyte count · score 0.26
- C-reactive protein measurement · score 0.23
- myeloid white cell count · score 0.22
- protein measurement · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96AX2-F1 | alphafold | PREDICTED | 83.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96AX2.
Amino-acid sequence (223 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB37?
The strongest Open Targets associations for RAB37 are platelet count, lymphocyte count, neurodegenerative disease, platelet crit and blood protein measurement.
How long is the RAB37 protein?
The Homo sapiens RAB37 protein (UniProt Q96AX2) is 223 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96AX2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96AX2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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