EEF1A lysine methyltransferase 3 (EEF1AKMT3)
Homo sapiens — UniProt Q96AZ1
Data last refreshed: (UniProt release unknown)
Key facts
EEF1A lysine methyltransferase 3 (EEF1AKMT3) is a protein from Homo sapiens identified by UniProt accession Q96AZ1, 226 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q96AZ1; gene symbol EEF1AKMT3.
- Organism: Homo sapiens.
- Length: 226 amino acids.
- Top disease associations (Open Targets): aspartate aminotransferase measurement, vitamin D-dependent rickets, type 1A and alkaline phosphatase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | EEF1A lysine methyltransferase 3 |
|---|---|
| UniProt accession | Q96AZ1 |
| Gene | EEF1AKMT3 |
| Organism | Homo sapiens |
| Length | 226 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- aspartate aminotransferase measurement · score 0.15
- vitamin D-dependent rickets, type 1A · score 0.11
- alkaline phosphatase measurement · score 0.09
- IGF-1 measurement · score 0.08
- body height · score 0.07
- sitting height measurement · score 0.06
- mathematical ability · score 0.06
- multiple sclerosis · score 0.06
- forced expiratory volume · score 0.04
- urate measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96AZ1-F1 | alphafold | PREDICTED | 90.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96AZ1.
Amino-acid sequence (226 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EEF1AKMT3?
The strongest Open Targets associations for EEF1AKMT3 are aspartate aminotransferase measurement, vitamin D-dependent rickets, type 1A, alkaline phosphatase measurement, IGF-1 measurement and body height.
How long is the EEF1AKMT3 protein?
The Homo sapiens EEF1AKMT3 protein (UniProt Q96AZ1) is 226 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96AZ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96AZ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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