Engulfment and cell motility protein 3 (ELMO3)
Homo sapiens — UniProt Q96BJ8
Data last refreshed: (UniProt release unknown)
Key facts
Engulfment and cell motility protein 3 (ELMO3) is a protein from Homo sapiens identified by UniProt accession Q96BJ8, 720 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.
- UniProt accession: Q96BJ8; gene symbol ELMO3.
- Organism: Homo sapiens.
- Length: 720 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, heel bone mineral density and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Engulfment and cell motility protein 3 |
|---|---|
| UniProt accession | Q96BJ8 |
| Gene | ELMO3 |
| Organism | Homo sapiens |
| Length | 720 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.24
- heel bone mineral density · score 0.22
- mean corpuscular hemoglobin concentration · score 0.17
- BMI-adjusted waist-hip ratio · score 0.16
- intraocular pressure measurement · score 0.16
- high density lipoprotein cholesterol measurement · score 0.15
- bone quantitative ultrasound measurement · score 0.15
- mean corpuscular hemoglobin · score 0.14
- mean reticulocyte volume · score 0.14
- appendicular lean mass · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BJ8-F1 | alphafold | PREDICTED | 88.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BJ8.
Amino-acid sequence (720 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELMO3?
The strongest Open Targets associations for ELMO3 are mean corpuscular volume, heel bone mineral density, mean corpuscular hemoglobin concentration, BMI-adjusted waist-hip ratio and intraocular pressure measurement.
How long is the ELMO3 protein?
The Homo sapiens ELMO3 protein (UniProt Q96BJ8) is 720 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BJ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BJ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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