PIN2/TERF1-interacting telomerase inhibitor 1 (PINX1)
Homo sapiens — UniProt Q96BK5
Data last refreshed: (UniProt release unknown)
Key facts
PIN2/TERF1-interacting telomerase inhibitor 1 (PINX1) is a protein from Homo sapiens identified by UniProt accession Q96BK5, 328 residues long. MolForge cross-references it against 0 known binders and 166 disease associations.
- UniProt accession: Q96BK5; gene symbol PINX1.
- Organism: Homo sapiens.
- Length: 328 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, neurodegenerative disease and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PIN2/TERF1-interacting telomerase inhibitor 1 |
|---|---|
| UniProt accession | Q96BK5 |
| Gene | PINX1 |
| Organism | Homo sapiens |
| Length | 328 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (166)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.31
- neurodegenerative disease · score 0.30
- lymphocyte count · score 0.29
- alkaline phosphatase measurement · score 0.28
- high density lipoprotein cholesterol measurement · score 0.26
- total blood protein measurement · score 0.24
- serum gamma-glutamyl transferase measurement · score 0.23
- apolipoprotein A 1 measurement · score 0.22
- mean corpuscular volume · score 0.22
- neutrophil count · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BK5-F1 | alphafold | PREDICTED | 64.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BK5.
Amino-acid sequence (328 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PINX1?
The strongest Open Targets associations for PINX1 are triglyceride measurement, neurodegenerative disease, lymphocyte count, alkaline phosphatase measurement and high density lipoprotein cholesterol measurement.
How long is the PINX1 protein?
The Homo sapiens PINX1 protein (UniProt Q96BK5) is 328 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BK5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BK5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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