ADP-ribosylation factor-like protein 8A (ARL8A)
Homo sapiens — UniProt Q96BM9
Data last refreshed: (UniProt release unknown)
Key facts
ADP-ribosylation factor-like protein 8A (ARL8A) is a protein from Homo sapiens identified by UniProt accession Q96BM9, 186 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q96BM9; gene symbol ARL8A.
- Organism: Homo sapiens.
- Length: 186 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body mass index and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ADP-ribosylation factor-like protein 8A |
|---|---|
| UniProt accession | Q96BM9 |
| Gene | ARL8A |
| Organism | Homo sapiens |
| Length | 186 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- body mass index · score 0.25
- blood protein measurement · score 0.22
- age at first sexual intercourse measurement · score 0.04
- breast cancer · score 0.00
- non-alcoholic steatohepatitis · score 0.00
- neoplasm · score 0.00
- meningococcal infection · score 0.00
- pancreatic ductal adenocarcinoma · score 0.00
- acute myeloid leukemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BM9-F1 | alphafold | PREDICTED | 92.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BM9.
Amino-acid sequence (186 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARL8A?
The strongest Open Targets associations for ARL8A are neurodegenerative disease, body mass index, blood protein measurement, age at first sexual intercourse measurement and breast cancer.
How long is the ARL8A protein?
The Homo sapiens ARL8A protein (UniProt Q96BM9) is 186 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BM9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BM9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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