Tripartite motif-containing protein 43 (TRIM43)
Homo sapiens — UniProt Q96BQ3
Data last refreshed: (UniProt release unknown)
Key facts
Tripartite motif-containing protein 43 (TRIM43) is a protein from Homo sapiens identified by UniProt accession Q96BQ3, 446 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q96BQ3; gene symbol TRIM43.
- Organism: Homo sapiens.
- Length: 446 amino acids.
- Top disease associations (Open Targets): eosinophil count, facioscapulohumeral muscular dystrophy and Facioscapulohumeral dystrophy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tripartite motif-containing protein 43 |
|---|---|
| UniProt accession | Q96BQ3 |
| Gene | TRIM43 |
| Organism | Homo sapiens |
| Length | 446 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.09
- facioscapulohumeral muscular dystrophy · score 0.01
- Facioscapulohumeral dystrophy · score 0.01
- Herpesviridae infectious disease · score 0.01
- hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BQ3-F1 | alphafold | PREDICTED | 88.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BQ3.
Amino-acid sequence (446 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRIM43?
The strongest Open Targets associations for TRIM43 are eosinophil count, facioscapulohumeral muscular dystrophy, Facioscapulohumeral dystrophy, Herpesviridae infectious disease and hepatocellular carcinoma.
How long is the TRIM43 protein?
The Homo sapiens TRIM43 protein (UniProt Q96BQ3) is 446 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BQ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BQ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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