Zinc finger protein 669 (ZNF669)
Homo sapiens — UniProt Q96BR6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 669 (ZNF669) is a protein from Homo sapiens identified by UniProt accession Q96BR6, 464 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q96BR6; gene symbol ZNF669.
- Organism: Homo sapiens.
- Length: 464 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, DNA methylation and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 669 |
|---|---|
| UniProt accession | Q96BR6 |
| Gene | ZNF669 |
| Organism | Homo sapiens |
| Length | 464 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- DNA methylation · score 0.05
- neurofibrillary tangles measurement · score 0.05
- mean corpuscular hemoglobin · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BR6-F1 | alphafold | PREDICTED | 65.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BR6.
Amino-acid sequence (464 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF669?
The strongest Open Targets associations for ZNF669 are neurodegenerative disease, DNA methylation, neurofibrillary tangles measurement and mean corpuscular hemoglobin.
How long is the ZNF669 protein?
The Homo sapiens ZNF669 protein (UniProt Q96BR6) is 464 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BR6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BR6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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