Zinc finger and BTB domain-containing protein 8A (ZBTB8A)
Homo sapiens — UniProt Q96BR9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and BTB domain-containing protein 8A (ZBTB8A) is a protein from Homo sapiens identified by UniProt accession Q96BR9, 441 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q96BR9; gene symbol ZBTB8A.
- Organism: Homo sapiens.
- Length: 441 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, drug use measurement and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 8A |
|---|---|
| UniProt accession | Q96BR9 |
| Gene | ZBTB8A |
| Organism | Homo sapiens |
| Length | 441 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- drug use measurement · score 0.03
- cancer · score 0.01
- gastric carcinoma · score 0.00
- gastric adenocarcinoma · score 0.00
- lymph node metastatic carcinoma · score 0.00
- neoplasm · score 0.00
- adenocarcinoma · score 0.00
- sialadenitis · score 0.00
- diabetes insipidus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BR9-F1 | alphafold | PREDICTED | 61.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BR9.
Amino-acid sequence (441 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZBTB8A?
The strongest Open Targets associations for ZBTB8A are neurodegenerative disease, drug use measurement, cancer, gastric carcinoma and gastric adenocarcinoma.
How long is the ZBTB8A protein?
The Homo sapiens ZBTB8A protein (UniProt Q96BR9) is 441 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BR9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BR9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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