Uracil phosphoribosyltransferase homolog (UPRT)
Homo sapiens — UniProt Q96BW1
Data last refreshed: (UniProt release unknown)
Key facts
Uracil phosphoribosyltransferase homolog (UPRT) is a protein from Homo sapiens identified by UniProt accession Q96BW1, 309 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q96BW1; gene symbol UPRT.
- Organism: Homo sapiens.
- Length: 309 amino acids.
- Top disease associations (Open Targets): vaginal discharge, neoplasm and candidiasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uracil phosphoribosyltransferase homolog |
|---|---|
| UniProt accession | Q96BW1 |
| Gene | UPRT |
| Organism | Homo sapiens |
| Length | 309 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- vaginal discharge · score 0.26
- neoplasm · score 0.01
- candidiasis · score 0.01
- infection · score 0.01
- infect · score 0.01
- Steinert myotonic dystrophy · score 0.01
- cancer · score 0.01
- glioblastoma · score 0.00
- vulvovaginal candidiasis · score 0.00
- glioblastoma multiforme · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BW1-F1 | alphafold | PREDICTED | 75.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BW1.
Amino-acid sequence (309 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UPRT?
The strongest Open Targets associations for UPRT are vaginal discharge, neoplasm, candidiasis, infection and infect.
How long is the UPRT protein?
The Homo sapiens UPRT protein (UniProt Q96BW1) is 309 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BW1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BW1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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