MOB kinase activator 3A (MOB3A)
Homo sapiens — UniProt Q96BX8
Data last refreshed: (UniProt release unknown)
Key facts
MOB kinase activator 3A (MOB3A) is a protein from Homo sapiens identified by UniProt accession Q96BX8, 217 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q96BX8; gene symbol MOB3A.
- Organism: Homo sapiens.
- Length: 217 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, adolescent idiopathic scoliosis and balding measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MOB kinase activator 3A |
|---|---|
| UniProt accession | Q96BX8 |
| Gene | MOB3A |
| Organism | Homo sapiens |
| Length | 217 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.19
- adolescent idiopathic scoliosis · score 0.04
- balding measurement · score 0.03
- leukocyte count · score 0.03
- Acute hepatic failure · score 0.01
- nonpapillary renal cell carcinoma · score 0.01
- osteosarcoma · score 0.01
- neoplasm · score 0.00
- ganglioneuroma · score 0.00
- attention deficit hyperactivity disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BX8-F1 | alphafold | PREDICTED | 89.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BX8.
Amino-acid sequence (217 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MOB3A?
The strongest Open Targets associations for MOB3A are neurodegenerative disease, adolescent idiopathic scoliosis, balding measurement, leukocyte count and Acute hepatic failure.
How long is the MOB3A protein?
The Homo sapiens MOB3A protein (UniProt Q96BX8) is 217 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BX8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BX8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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