Leukocyte receptor cluster member 1 (LENG1)
Homo sapiens — UniProt Q96BZ8
Data last refreshed: (UniProt release unknown)
Key facts
Leukocyte receptor cluster member 1 (LENG1) is a protein from Homo sapiens identified by UniProt accession Q96BZ8, 264 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q96BZ8; gene symbol LENG1.
- Organism: Homo sapiens.
- Length: 264 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, intellectual developmental disorder with speech delay, autism and dysmorphic facies and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leukocyte receptor cluster member 1 |
|---|---|
| UniProt accession | Q96BZ8 |
| Gene | LENG1 |
| Organism | Homo sapiens |
| Length | 264 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- intellectual developmental disorder with speech delay, autism and dysmorphic facies · score 0.27
- genetic disorder · score 0.12
- phosphatidylinositol measurement · score 0.05
- phosphatidylcholine measurement · score 0.04
- alkaline phosphatase measurement · score 0.03
- diacylglycerol 38:4 measurement · score 0.03
- viral load · score 0.03
- vitamin D measurement · score 0.03
- infection · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BZ8-F1 | alphafold | PREDICTED | 74.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BZ8.
Amino-acid sequence (264 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LENG1?
The strongest Open Targets associations for LENG1 are neurodegenerative disease, intellectual developmental disorder with speech delay, autism and dysmorphic facies, genetic disorder, phosphatidylinositol measurement and phosphatidylcholine measurement.
How long is the LENG1 protein?
The Homo sapiens LENG1 protein (UniProt Q96BZ8) is 264 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BZ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BZ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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