TBC1 domain family member 20 (TBC1D20)
Homo sapiens — UniProt Q96BZ9
Data last refreshed: (UniProt release unknown)
Key facts
TBC1 domain family member 20 (TBC1D20) is a protein from Homo sapiens identified by UniProt accession Q96BZ9, 403 residues long. MolForge cross-references it against 0 known binders and 177 disease associations.
- UniProt accession: Q96BZ9; gene symbol TBC1D20.
- Organism: Homo sapiens.
- Length: 403 amino acids.
- Top disease associations (Open Targets): Micro syndrome, neurodegenerative disease and Global developmental delay.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TBC1 domain family member 20 |
|---|---|
| UniProt accession | Q96BZ9 |
| Gene | TBC1D20 |
| Organism | Homo sapiens |
| Length | 403 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (177)
Diseases linked to this target (Open Targets).
- Micro syndrome · score 0.77
- neurodegenerative disease · score 0.51
- Global developmental delay · score 0.37
- Hepatitis · score 0.37
- Intellectual disability · score 0.37
- genetic disorder · score 0.34
- lysosomal storage disease · score 0.22
- Seizure · score 0.18
- breast adenocarcinoma · score 0.10
- azoospermia · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96BZ9-F1 | alphafold | PREDICTED | 81.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96BZ9.
Amino-acid sequence (403 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TBC1D20?
The strongest Open Targets associations for TBC1D20 are Micro syndrome, neurodegenerative disease, Global developmental delay, Hepatitis and Intellectual disability.
How long is the TBC1D20 protein?
The Homo sapiens TBC1D20 protein (UniProt Q96BZ9) is 403 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96BZ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96BZ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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