Synaptotagmin-like protein 4 (SYTL4)
Homo sapiens — UniProt Q96C24
Data last refreshed: (UniProt release unknown)
Key facts
Synaptotagmin-like protein 4 (SYTL4) is a protein from Homo sapiens identified by UniProt accession Q96C24, 671 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q96C24; gene symbol SYTL4.
- Organism: Homo sapiens.
- Length: 671 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, neuroinflammatory disorder and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptotagmin-like protein 4 |
|---|---|
| UniProt accession | Q96C24 |
| Gene | SYTL4 |
| Organism | Homo sapiens |
| Length | 671 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.25
- neuroinflammatory disorder · score 0.18
- glioblastoma multiforme · score 0.14
- MODY · score 0.11
- type 2 diabetes mellitus · score 0.09
- diabetes mellitus, transient neonatal, 2 · score 0.08
- triple-negative breast cancer · score 0.07
- type 1 diabetes mellitus · score 0.07
- growth hormone-secreting pituitary adenoma · score 0.07
- Pituitary Gland Adenoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96C24-F1 | alphafold | PREDICTED | 67.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96C24.
Amino-acid sequence (671 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYTL4?
The strongest Open Targets associations for SYTL4 are breast adenocarcinoma, neuroinflammatory disorder, glioblastoma multiforme, MODY and type 2 diabetes mellitus.
How long is the SYTL4 protein?
The Homo sapiens SYTL4 protein (UniProt Q96C24) is 671 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96C24 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96C24 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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