ELL-associated factor 2 (EAF2)
Homo sapiens — UniProt Q96CJ1
Data last refreshed: (UniProt release unknown)
Key facts
ELL-associated factor 2 (EAF2) is a protein from Homo sapiens identified by UniProt accession Q96CJ1, 260 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q96CJ1; gene symbol EAF2.
- Organism: Homo sapiens.
- Length: 260 amino acids.
- Top disease associations (Open Targets): childhood onset asthma, asthma and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ELL-associated factor 2 |
|---|---|
| UniProt accession | Q96CJ1 |
| Gene | EAF2 |
| Organism | Homo sapiens |
| Length | 260 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- childhood onset asthma · score 0.17
- asthma · score 0.15
- multiple sclerosis · score 0.14
- platelet count · score 0.12
- Senior-Loken syndrome · score 0.12
- age-related hearing impairment · score 0.11
- mean corpuscular hemoglobin concentration · score 0.10
- high density lipoprotein cholesterol measurement · score 0.08
- diet measurement · score 0.08
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96CJ1-F1 | alphafold | PREDICTED | 70.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96CJ1.
Amino-acid sequence (260 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EAF2?
The strongest Open Targets associations for EAF2 are childhood onset asthma, asthma, multiple sclerosis, platelet count and Senior-Loken syndrome.
How long is the EAF2 protein?
The Homo sapiens EAF2 protein (UniProt Q96CJ1) is 260 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96CJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96CJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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