Isochorismatase domain-containing protein 1 (ISOC1)
Homo sapiens — UniProt Q96CN7
Data last refreshed: (UniProt release unknown)
Key facts
Isochorismatase domain-containing protein 1 (ISOC1) is a protein from Homo sapiens identified by UniProt accession Q96CN7, 298 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q96CN7; gene symbol ISOC1.
- Organism: Homo sapiens.
- Length: 298 amino acids.
- Top disease associations (Open Targets): neurofibrillary tangles measurement, Pilonidal abscess and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Isochorismatase domain-containing protein 1 |
|---|---|
| UniProt accession | Q96CN7 |
| Gene | ISOC1 |
| Organism | Homo sapiens |
| Length | 298 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurofibrillary tangles measurement · score 0.28
- Pilonidal abscess · score 0.11
- neoplasm · score 0.09
- non-small cell lung carcinoma · score 0.08
- base metabolic rate measurement · score 0.07
- PR interval · score 0.06
- refractive error measurement · score 0.05
- diet measurement · score 0.05
- in situ carcinoma · score 0.04
- Red cell distribution width · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96CN7-F1 | alphafold | PREDICTED | 89.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96CN7.
Amino-acid sequence (298 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ISOC1?
The strongest Open Targets associations for ISOC1 are neurofibrillary tangles measurement, Pilonidal abscess, neoplasm, non-small cell lung carcinoma and base metabolic rate measurement.
How long is the ISOC1 protein?
The Homo sapiens ISOC1 protein (UniProt Q96CN7) is 298 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96CN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96CN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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