GRIP and coiled-coil domain-containing protein 1 (GCC1)
Homo sapiens — UniProt Q96CN9
Data last refreshed: (UniProt release unknown)
Key facts
GRIP and coiled-coil domain-containing protein 1 (GCC1) is a protein from Homo sapiens identified by UniProt accession Q96CN9, 775 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q96CN9; gene symbol GCC1.
- Organism: Homo sapiens.
- Length: 775 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, intelligence and cognitive function measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GRIP and coiled-coil domain-containing protein 1 |
|---|---|
| UniProt accession | Q96CN9 |
| Gene | GCC1 |
| Organism | Homo sapiens |
| Length | 775 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- intelligence · score 0.19
- cognitive function measurement · score 0.19
- type 2 diabetes mellitus · score 0.18
- Abnormality of refraction · score 0.09
- self reported educational attainment · score 0.06
- Cleft palate · score 0.02
- aspartate aminotransferase measurement · score 0.02
- triglyceride measurement · score 0.02
- bladder transitional cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96CN9-F1 | alphafold | PREDICTED | 76.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96CN9.
Amino-acid sequence (775 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GCC1?
The strongest Open Targets associations for GCC1 are neurodegenerative disease, intelligence, cognitive function measurement, type 2 diabetes mellitus and Abnormality of refraction.
How long is the GCC1 protein?
The Homo sapiens GCC1 protein (UniProt Q96CN9) is 775 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96CN9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96CN9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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