Leucine-rich repeat-containing protein 58 (LRRC58)
Homo sapiens — UniProt Q96CX6
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 58 (LRRC58) is a protein from Homo sapiens identified by UniProt accession Q96CX6, 371 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q96CX6; gene symbol LRRC58.
- Organism: Homo sapiens.
- Length: 371 amino acids.
- Top disease associations (Open Targets): refractive error measurement, appendicular lean mass and ulcerative colitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 58 |
|---|---|
| UniProt accession | Q96CX6 |
| Gene | LRRC58 |
| Organism | Homo sapiens |
| Length | 371 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.13
- appendicular lean mass · score 0.09
- ulcerative colitis · score 0.01
- myeloid sarcoma · score 0.00
- prostate cancer · score 0.00
- invasive breast ductal carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96CX6-F1 | alphafold | PREDICTED | 77.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96CX6.
Amino-acid sequence (371 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC58?
The strongest Open Targets associations for LRRC58 are refractive error measurement, appendicular lean mass, ulcerative colitis, myeloid sarcoma and prostate cancer.
How long is the LRRC58 protein?
The Homo sapiens LRRC58 protein (UniProt Q96CX6) is 371 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96CX6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96CX6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.