U8 snoRNA-decapping enzyme (NUDT16)
Homo sapiens — UniProt Q96DE0
Data last refreshed: (UniProt release unknown)
Key facts
U8 snoRNA-decapping enzyme (NUDT16) is a protein from Homo sapiens identified by UniProt accession Q96DE0, 195 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q96DE0; gene symbol NUDT16.
- Organism: Homo sapiens.
- Length: 195 amino acids.
- Top disease associations (Open Targets): smoking behaviour measurement, Sepsis and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | U8 snoRNA-decapping enzyme |
|---|---|
| UniProt accession | Q96DE0 |
| Gene | NUDT16 |
| Organism | Homo sapiens |
| Length | 195 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- smoking behaviour measurement · score 0.06
- Sepsis · score 0.04
- neoplasm · score 0.04
- hepatocellular carcinoma · score 0.03
- cancer · score 0.03
- blood phosphate measurement · score 0.03
- smoking behavior · score 0.03
- insulin resistance · score 0.02
- Huntington disease · score 0.02
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96DE0-F1 | alphafold | PREDICTED | 92.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DE0.
Amino-acid sequence (195 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NUDT16?
The strongest Open Targets associations for NUDT16 are smoking behaviour measurement, Sepsis, neoplasm, hepatocellular carcinoma and cancer.
How long is the NUDT16 protein?
The Homo sapiens NUDT16 protein (UniProt Q96DE0) is 195 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96DE0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96DE0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.