NXPE family member 2 (NXPE2)
Homo sapiens — UniProt Q96DL1
Data last refreshed: (UniProt release unknown)
Key facts
NXPE family member 2 (NXPE2) is a protein from Homo sapiens identified by UniProt accession Q96DL1, 559 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q96DL1; gene symbol NXPE2.
- Organism: Homo sapiens.
- Length: 559 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, gut microbiome measurement and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NXPE family member 2 |
|---|---|
| UniProt accession | Q96DL1 |
| Gene | NXPE2 |
| Organism | Homo sapiens |
| Length | 559 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.22
- gut microbiome measurement · score 0.12
- body mass index · score 0.06
- inflammatory skin disease · score 0.03
- heel bone mineral density · score 0.03
- bone quantitative ultrasound measurement · score 0.03
- smoking behavior · score 0.03
- age at menarche · score 0.03
- waist circumference · score 0.02
- bone density · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96DL1-F1 | alphafold | PREDICTED | 89.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DL1.
Amino-acid sequence (559 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NXPE2?
The strongest Open Targets associations for NXPE2 are PHF-tau measurement, gut microbiome measurement, body mass index, inflammatory skin disease and heel bone mineral density.
How long is the NXPE2 protein?
The Homo sapiens NXPE2 protein (UniProt Q96DL1) is 559 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96DL1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96DL1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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