SLAM family member 6 (SLAMF6)
Homo sapiens — UniProt Q96DU3
Data last refreshed: (UniProt release unknown)
Key facts
SLAM family member 6 (SLAMF6) is a protein from Homo sapiens identified by UniProt accession Q96DU3, 332 residues long. MolForge cross-references it against 0 known binders and 160 disease associations.
- UniProt accession: Q96DU3; gene symbol SLAMF6.
- Organism: Homo sapiens.
- Length: 332 amino acids.
- Top disease associations (Open Targets): Graves disease, hypothyroidism and myxedema.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SLAM family member 6 |
|---|---|
| UniProt accession | Q96DU3 |
| Gene | SLAMF6 |
| Organism | Homo sapiens |
| Length | 332 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (160)
Diseases linked to this target (Open Targets).
- Graves disease · score 0.30
- hypothyroidism · score 0.19
- myxedema · score 0.19
- thyroid disease · score 0.19
- pancreatic adenocarcinoma · score 0.18
- rheumatoid arthritis · score 0.16
- BMI-adjusted waist-hip ratio · score 0.11
- neoplasm · score 0.10
- neutrophil count · score 0.09
- leukocyte count · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96DU3-F1 | alphafold | PREDICTED | 77.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DU3.
Amino-acid sequence (332 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLAMF6?
The strongest Open Targets associations for SLAMF6 are Graves disease, hypothyroidism, myxedema, thyroid disease and pancreatic adenocarcinoma.
How long is the SLAMF6 protein?
The Homo sapiens SLAMF6 protein (UniProt Q96DU3) is 332 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96DU3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96DU3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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