Polyadenylate-binding protein 5 (PABPC5)
Homo sapiens — UniProt Q96DU9
Data last refreshed: (UniProt release unknown)
Key facts
Polyadenylate-binding protein 5 (PABPC5) is a protein from Homo sapiens identified by UniProt accession Q96DU9, 382 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q96DU9; gene symbol PABPC5.
- Organism: Homo sapiens.
- Length: 382 amino acids.
- Top disease associations (Open Targets): glycoprotein storage disease, hemoglobin H disease and hemoglobin C-beta-thalassemia syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polyadenylate-binding protein 5 |
|---|---|
| UniProt accession | Q96DU9 |
| Gene | PABPC5 |
| Organism | Homo sapiens |
| Length | 382 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- glycoprotein storage disease · score 0.04
- hemoglobin H disease · score 0.04
- hemoglobin C-beta-thalassemia syndrome · score 0.04
- dominant beta-thalassemia · score 0.04
- neuronal ceroid lipofuscinosis 1 · score 0.04
- combined immunodeficiency due to OX40 deficiency · score 0.03
- Hyperlipoproteinemia type 1 · score 0.03
- erythroleukemia, familial, susceptibility to · score 0.03
- hemolytic anemia due to diphosphoglycerate mutase deficiency · score 0.03
- hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96DU9-F1 | alphafold | PREDICTED | 91.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DU9.
Amino-acid sequence (382 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PABPC5?
The strongest Open Targets associations for PABPC5 are glycoprotein storage disease, hemoglobin H disease, hemoglobin C-beta-thalassemia syndrome, dominant beta-thalassemia and neuronal ceroid lipofuscinosis 1.
How long is the PABPC5 protein?
The Homo sapiens PABPC5 protein (UniProt Q96DU9) is 382 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96DU9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96DU9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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