Large ribosomal subunit protein mL38 (MRPL38)
Homo sapiens — UniProt Q96DV4
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein mL38 (MRPL38) is a protein from Homo sapiens identified by UniProt accession Q96DV4, 380 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q96DV4; gene symbol MRPL38.
- Organism: Homo sapiens.
- Length: 380 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, white matter hyperintensity measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein mL38 |
|---|---|
| UniProt accession | Q96DV4 |
| Gene | MRPL38 |
| Organism | Homo sapiens |
| Length | 380 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- white matter hyperintensity measurement · score 0.22
- mean platelet volume · score 0.10
- systolic blood pressure · score 0.09
- hypertension · score 0.08
- body mass index · score 0.08
- pulse pressure measurement · score 0.07
- brain measurement · score 0.06
- low density lipoprotein cholesterol measurement · score 0.06
- platelet count · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96DV4-F1 | alphafold | PREDICTED | 82.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DV4.
Amino-acid sequence (380 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL38?
The strongest Open Targets associations for MRPL38 are neurodegenerative disease, white matter hyperintensity measurement, mean platelet volume, systolic blood pressure and hypertension.
How long is the MRPL38 protein?
The Homo sapiens MRPL38 protein (UniProt Q96DV4) is 380 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96DV4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96DV4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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