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Dynein regulatory complex subunit 10 (DRC10)

Homo sapiens — UniProt Q96DY2

Gene: DRC10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Dynein regulatory complex subunit 10 (DRC10) is a protein from Homo sapiens identified by UniProt accession Q96DY2, 449 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

  • UniProt accession: Q96DY2; gene symbol DRC10.
  • Organism: Homo sapiens.
  • Length: 449 amino acids.
  • Top disease associations (Open Targets): body mass index, response to fenofibrate and blood protein measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameDynein regulatory complex subunit 10
UniProt accessionQ96DY2
GeneDRC10
OrganismHomo sapiens
Length449 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (9)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.07
  • response to fenofibrate · score 0.07
  • blood protein measurement · score 0.04
  • platelet count · score 0.03
  • urate measurement · score 0.03
  • bone density · score 0.03
  • nasopharyngeal neoplasm · score 0.01
  • glioblastoma multiforme · score 0.00
  • chronic rhinosinusitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96DY2-F1alphafoldPREDICTED81.46—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DY2.

Amino-acid sequence (449 residues)

MALDILAMAP LYQAPAINRI GPKTDPSKRP ADPLKPLVLS RTKLTTIEAK RIMSILDEAI YKVELVTLLS YVASNREDME GMLGEDVMRA VREHEDLCQV LLENVRCLKE KERQLQEQKE AEEEGWLRDR LLSIELQKSS LSPLMQQIKD STKNVLRLLL SNPQAARLLQ MQTQGRSAEA QNFIDSLIEL RGFLFEKLLT SPMEARDKAQ FLQDISRQNS NNQQIIDTLE KELAERMKNR NAEVEKENFV IQELKNHLHQ VLKFSENSLV RTKQEAEKQQ KADFRASQAR VAKIQQEILQ LQSQFYNLVM ENREAEQALR KKKYKVETEI ENWIQKYDTE MGEKQEELED LDAVHREEKI SLEELRRRHK VLVGEFAQIR EEREINSKKR MEAEQEMVRM VRAATLIQAL WKGYLVRSLL RSKKKRGKGK AKDKEKGKQK GKEKGKGKK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with DRC10?

The strongest Open Targets associations for DRC10 are body mass index, response to fenofibrate, blood protein measurement, platelet count and urate measurement.

How long is the DRC10 protein?

The Homo sapiens DRC10 protein (UniProt Q96DY2) is 449 amino acids long.

Browse: Targets: D · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ96DY2
GeneDRC10
OrganismHomo sapiens
Length449
Binders0
Diseases9
View on UniProt