CAP-Gly domain-containing linker protein 3 (CLIP3)
Homo sapiens — UniProt Q96DZ5
Data last refreshed: (UniProt release unknown)
Key facts
CAP-Gly domain-containing linker protein 3 (CLIP3) is a protein from Homo sapiens identified by UniProt accession Q96DZ5, 547 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q96DZ5; gene symbol CLIP3.
- Organism: Homo sapiens.
- Length: 547 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, glioblastoma multiforme and lethal congenital contracture syndrome 3.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CAP-Gly domain-containing linker protein 3 |
|---|---|
| UniProt accession | Q96DZ5 |
| Gene | CLIP3 |
| Organism | Homo sapiens |
| Length | 547 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- glioblastoma multiforme · score 0.07
- lethal congenital contracture syndrome 3 · score 0.03
- chronic lymphocytic leukemia · score 0.02
- membranous glomerulonephritis · score 0.02
- insulin resistance · score 0.02
- periodontitis · score 0.01
- glioblastoma · score 0.01
- endometrial carcinoma · score 0.01
- cholangiocarcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96DZ5-F1 | alphafold | PREDICTED | 74.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DZ5.
Amino-acid sequence (547 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLIP3?
The strongest Open Targets associations for CLIP3 are neurodegenerative disease, glioblastoma multiforme, lethal congenital contracture syndrome 3, chronic lymphocytic leukemia and membranous glomerulonephritis.
How long is the CLIP3 protein?
The Homo sapiens CLIP3 protein (UniProt Q96DZ5) is 547 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96DZ5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96DZ5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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