Transmembrane 4 L6 family member 19 (TM4SF19)

About Transmembrane 4 L6 family member 19

Transmembrane 4 L6 family member 19 (TM4SF19) is a protein from Homo sapiens identified by UniProt accession Q96DZ7, 209 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Transmembrane 4 L6 family member 19
UniProt accession	Q96DZ7
Gene	TM4SF19
Organism	Homo sapiens
Length	209 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

C-reactive protein measurement · score 0.21
platelet component distribution width · score 0.13
mean platelet volume · score 0.13
genetic disorder · score 0.12
lean body mass · score 0.11
self reported educational attainment · score 0.08
head and neck squamous cell carcinoma · score 0.07
high density lipoprotein cholesterol measurement · score 0.07
vital capacity · score 0.06
fat body mass · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96DZ7-F1	alphafold	PREDICTED	82.41	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DZ7.

Amino-acid sequence (209 residues)

MVSSPCTQAS SRTCSRILGL SLGTAALFAA GANVALLLPN WDVTYLLRGL LGRHAMLGTG LWGGGLMVLT AAILISLMGW RYGCFSKSGL CRSVLTALLS GGLALLGALI CFVTSGVALK DGPFCMFDVS SFNQTQAWKY GYPFKDLHSR NYLYDRSLWN SVCLEPSAAV VWHVSLFSAL LCISLLQLLL VVVHVINSLL GLFCSLCEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards