CKLF-like MARVEL transmembrane domain-containing protein 5 (CMTM5)
Homo sapiens — UniProt Q96DZ9
Data last refreshed: (UniProt release unknown)
Key facts
CKLF-like MARVEL transmembrane domain-containing protein 5 (CMTM5) is a protein from Homo sapiens identified by UniProt accession Q96DZ9, 223 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q96DZ9; gene symbol CMTM5.
- Organism: Homo sapiens.
- Length: 223 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, renal cell carcinoma and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CKLF-like MARVEL transmembrane domain-containing protein 5 |
|---|---|
| UniProt accession | Q96DZ9 |
| Gene | CMTM5 |
| Organism | Homo sapiens |
| Length | 223 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.09
- renal cell carcinoma · score 0.06
- systolic blood pressure · score 0.05
- heart rate · score 0.04
- neoplasm · score 0.04
- electrocardiography · score 0.04
- diet measurement · score 0.04
- atrial flutter · score 0.03
- pulse pressure measurement · score 0.03
- experimental autoimmune encephalomyelitis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96DZ9-F1 | alphafold | PREDICTED | 59.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96DZ9.
Amino-acid sequence (223 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CMTM5?
The strongest Open Targets associations for CMTM5 are hepatocellular carcinoma, renal cell carcinoma, systolic blood pressure, heart rate and neoplasm.
How long is the CMTM5 protein?
The Homo sapiens CMTM5 protein (UniProt Q96DZ9) is 223 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96DZ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96DZ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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