About Ras-related protein Rab-3C
Ras-related protein Rab-3C (RAB3C) is a protein
from Homo sapiens identified by UniProt accession
Q96E17, 227 residues long.
MolForge cross-references it against 0 known binders and
77 disease associations.
Target properties
| Protein name | Ras-related protein Rab-3C |
|---|
| UniProt accession | Q96E17 |
|---|
| Gene | RAB3C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 227 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (77)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- PHF-tau measurement · score 0.40
- gut microbiome measurement · score 0.36
- DNA methylation · score 0.33
- type 1 diabetes mellitus · score 0.27
- type 2 diabetes mellitus · score 0.25
- Hernia · score 0.25
- breast carcinoma · score 0.20
- forced expiratory volume · score 0.19
- response to gases and fumes exposure · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96E17-F1 | alphafold | PREDICTED | 82.62 | — |
Amino-acid sequence (227 residues)
MRHEAPMQMA SAQDARYGQK DSSDQNFDYM FKLLIIGNSS VGKTSFLFRY ADDSFTSAFV STVGIDFKVK TVFKNEKRIK LQIWDTAGQE RYRTITTAYY RGAMGFILMY DITNEESFNA VQDWSTQIKT YSWDNAQVIL VGNKCDMEDE RVISTERGQH LGEQLGFEFF ETSAKDNINV KQTFERLVDI ICDKMSESLE TDPAITAAKQ NTRLKETPPP PQPNCAC
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