Ras-related protein Rab-3C (RAB3C)
Homo sapiens — UniProt Q96E17
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-3C (RAB3C) is a protein from Homo sapiens identified by UniProt accession Q96E17, 227 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: Q96E17; gene symbol RAB3C.
- Organism: Homo sapiens.
- Length: 227 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, PHF-tau measurement and gut microbiome measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-3C |
|---|---|
| UniProt accession | Q96E17 |
| Gene | RAB3C |
| Organism | Homo sapiens |
| Length | 227 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- PHF-tau measurement · score 0.40
- gut microbiome measurement · score 0.36
- DNA methylation · score 0.33
- type 1 diabetes mellitus · score 0.27
- type 2 diabetes mellitus · score 0.25
- Hernia · score 0.25
- breast carcinoma · score 0.20
- forced expiratory volume · score 0.19
- response to gases and fumes exposure · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96E17-F1 | alphafold | PREDICTED | 82.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96E17.
Amino-acid sequence (227 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB3C?
The strongest Open Targets associations for RAB3C are neurodegenerative disease, PHF-tau measurement, gut microbiome measurement, DNA methylation and type 1 diabetes mellitus.
How long is the RAB3C protein?
The Homo sapiens RAB3C protein (UniProt Q96E17) is 227 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96E17 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96E17 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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