Sperm acrosome-associated protein 9 (SPACA9)

About Sperm acrosome-associated protein 9

Sperm acrosome-associated protein 9 (SPACA9) is a protein from Homo sapiens identified by UniProt accession Q96E40, 222 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Sperm acrosome-associated protein 9
UniProt accession	Q96E40
Gene	SPACA9
Organism	Homo sapiens
Length	222 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

lifestyle measurement · score 0.15
Red cell distribution width · score 0.15
mathematical ability · score 0.14
self reported educational attainment · score 0.11
urate measurement · score 0.11
mean corpuscular volume · score 0.06
mean corpuscular hemoglobin concentration · score 0.05
Immature Reticulocyte Fraction Measurement · score 0.05
mean reticulocyte volume · score 0.05
mean platelet volume · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96E40-F1	alphafold	PREDICTED	80.29	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96E40.

Amino-acid sequence (222 residues)

MNEVKESLRS IEQKYKLFQQ QQLTFTAALE HCRENAHDKI RPISSIGQVQ SYMEHYCNSS TDRRVLLMFL DICSELNKLC QHFEAVHSGT PVTNNLLEKC KTLVSQSNDL SSLRAKYPHD VVNHLSCDEA RNHYGGVVSL IPLILDLMKE WIAHSEKLPR KVLQHVSEPQ AHQESTRGAA RPAQAIGTQP RATKHKCRQL TKASLKPRGC SKPPWRPPGG KL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards