F-box only protein 17 (FBXO17)
Homo sapiens — UniProt Q96EF6
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 17 (FBXO17) is a protein from Homo sapiens identified by UniProt accession Q96EF6, 278 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q96EF6; gene symbol FBXO17.
- Organism: Homo sapiens.
- Length: 278 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, body height and sitting height measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 17 |
|---|---|
| UniProt accession | Q96EF6 |
| Gene | FBXO17 |
| Organism | Homo sapiens |
| Length | 278 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.19
- body height · score 0.13
- sitting height measurement · score 0.12
- lean body mass · score 0.05
- fat body mass · score 0.05
- whole body water mass · score 0.04
- neoplasm · score 0.04
- hepatocellular carcinoma · score 0.04
- serum gamma-glutamyl transferase measurement · score 0.03
- base metabolic rate measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EF6-F1 | alphafold | PREDICTED | 90.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EF6.
Amino-acid sequence (278 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXO17?
The strongest Open Targets associations for FBXO17 are diastolic blood pressure, body height, sitting height measurement, lean body mass and fat body mass.
How long is the FBXO17 protein?
The Homo sapiens FBXO17 protein (UniProt Q96EF6) is 278 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EF6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EF6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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