Transcription elongation factor A protein-like 4 (TCEAL4)
Homo sapiens — UniProt Q96EI5
Data last refreshed: (UniProt release unknown)
Key facts
Transcription elongation factor A protein-like 4 (TCEAL4) is a protein from Homo sapiens identified by UniProt accession Q96EI5, 215 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q96EI5; gene symbol TCEAL4.
- Organism: Homo sapiens.
- Length: 215 amino acids.
- Top disease associations (Open Targets): Abnormal sperm morphology, cancer and systemic juvenile idiopathic arthritis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription elongation factor A protein-like 4 |
|---|---|
| UniProt accession | Q96EI5 |
| Gene | TCEAL4 |
| Organism | Homo sapiens |
| Length | 215 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- Abnormal sperm morphology · score 0.02
- cancer · score 0.02
- systemic juvenile idiopathic arthritis · score 0.01
- Thyroid Gland Undifferentiated (Anaplastic) Carcinoma · score 0.01
- Ehlers-Danlos syndrome, musculocontractural type · score 0.01
- papillary thyroid carcinoma · score 0.01
- glioblastoma multiforme · score 0.01
- renal cell carcinoma · score 0.00
- neuroblastoma · score 0.00
- multiple myeloma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EI5-F1 | alphafold | PREDICTED | 60.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EI5.
Amino-acid sequence (215 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TCEAL4?
The strongest Open Targets associations for TCEAL4 are Abnormal sperm morphology, cancer, systemic juvenile idiopathic arthritis, Thyroid Gland Undifferentiated (Anaplastic) Carcinoma and Ehlers-Danlos syndrome, musculocontractural type.
How long is the TCEAL4 protein?
The Homo sapiens TCEAL4 protein (UniProt Q96EI5) is 215 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EI5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EI5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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