PHD finger protein 21B (PHF21B)
Homo sapiens — UniProt Q96EK2
Data last refreshed: (UniProt release unknown)
Key facts
PHD finger protein 21B (PHF21B) is a protein from Homo sapiens identified by UniProt accession Q96EK2, 531 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q96EK2; gene symbol PHF21B.
- Organism: Homo sapiens.
- Length: 531 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, binge eating and chronic myeloproliferative disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PHD finger protein 21B |
|---|---|
| UniProt accession | Q96EK2 |
| Gene | PHF21B |
| Organism | Homo sapiens |
| Length | 531 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.27
- binge eating · score 0.07
- chronic myeloproliferative disorder · score 0.04
- linear and whorled nevoid hypermelanosis · score 0.04
- idiopathic hypereosinophilic syndrome · score 0.04
- metabolite measurement · score 0.04
- neoplasm · score 0.04
- eosinophil peroxidase deficiency · score 0.04
- neutropenia, severe congenital, 1, autosomal dominant · score 0.04
- ichthyosis prematurity syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EK2-F1 | alphafold | PREDICTED | 59.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EK2.
Amino-acid sequence (531 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PHF21B?
The strongest Open Targets associations for PHF21B are PHF-tau measurement, binge eating, chronic myeloproliferative disorder, linear and whorled nevoid hypermelanosis and idiopathic hypereosinophilic syndrome.
How long is the PHF21B protein?
The Homo sapiens PHF21B protein (UniProt Q96EK2) is 531 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EK2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EK2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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