KIF-binding protein (KIFBP)
Homo sapiens — UniProt Q96EK5
Data last refreshed: (UniProt release unknown)
Key facts
KIF-binding protein (KIFBP) is a protein from Homo sapiens identified by UniProt accession Q96EK5, 621 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q96EK5; gene symbol KIFBP.
- Organism: Homo sapiens.
- Length: 621 amino acids.
- Top disease associations (Open Targets): Goldberg-Shprintzen syndrome, peripheral neuropathy and eosinophil percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | KIF-binding protein |
|---|---|
| UniProt accession | Q96EK5 |
| Gene | KIFBP |
| Organism | Homo sapiens |
| Length | 621 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- Goldberg-Shprintzen syndrome · score 0.72
- peripheral neuropathy · score 0.12
- eosinophil percentage of leukocytes · score 0.08
- eosinophil count · score 0.06
- pseudohypoaldosteronism type 2B · score 0.04
- pseudohypoaldosteronism type 2D · score 0.04
- pseudohypoaldosteronism type 2E · score 0.03
- platelet component distribution width · score 0.02
- diabetes mellitus · score 0.02
- mean platelet volume · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EK5-F1 | alphafold | PREDICTED | 90.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EK5.
Amino-acid sequence (621 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KIFBP?
The strongest Open Targets associations for KIFBP are Goldberg-Shprintzen syndrome, peripheral neuropathy, eosinophil percentage of leukocytes, eosinophil count and pseudohypoaldosteronism type 2B.
How long is the KIFBP protein?
The Homo sapiens KIFBP protein (UniProt Q96EK5) is 621 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EK5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EK5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.